Program

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Nearly a decade has passed since the inaugural OEESC took place in 2002 in Washington, DC. Significant progress has been made with regards to knowledge and awareness of dermal exposure and diseases. The OEESCs with their multidisciplinary approach and plenary sessions have contributed substantially to knowledge exchange between researchers and practitioners around the world. Although many of these themes will look familiar, for each of the plenary sessions, the goal is to have keynote speakers summarize advancements achieved during the decade of progress and provide their vision for the decade of promise where the ultimate goal is delivering the science (ie., knowledge exchange) in a form the practitioner can readily implement.

SUNDAY, JUNE 5, 2011

08:00 Registration
Victoria University
at the University of Toronto
73 Queen’s Park Crescent                       MAP
09:00 Clinical Workshop
To include: diagnosis, patch testing, management, interesting cases,Workshop Leads:

  • Rosemary Nixon, MD (Australia)
  • Melanie Pratt, MD (Canada)
  • Swen John, MD (Germany)
Diagnosis of Occupational Contact Dermatitis – Rosemary Nixon

Interesting Cases from the Ottawa Hospital Patch Test Clinic – Melanie Pratt

Prevention of Occupational Skin Disease in a Clinical and International Context – Swen John

10:30-11:00 Break
11:00 Oral Abstract Presentations
(10 minute presentations with 2 – 5 minutes for questions)
3812    Variation in allergen content over time of acrylates/methacrylates in patch test preparations

3837/3847  The Impact of a Multidisciplinary Team and a Dedicated Return to Work Coordinator for Workers with Work-Related Skin Disease

3851    An integrated inpatient/outpatient rehabilitation program – the German approach

3859    Patient Safety Tools Including Check Lists in Occupational Medicine and Dermatology

12:00 Lunch (not provided)
13:00 Welcome
Conference Co-Chairs: Linn Holness and Irena Kudla
Oral Abstract Presentation as part of welcome
3843  Knowledge translation of research in occupational skin disease – the CREOD experience
13:30 Plenary Welcome
Plenary Session 1 Defining the Problem, Health Effects, Burden of Disease, Causation & Outcomes
The goal of the keynote(s) for this session will be to summarize the current state-of-the art knowledge with respect to burden of disease, causation and outcomes.
Future expectations/challenges will be presented.

Chair: Melanie Pratt (Canada)

13:30 Keynote 1
Health Effects, Causative Agents & Burden of Disease, Causation & Outcomes
Thomas Diepgen, MD (Germany)
14:15 Keynote 2
Outcomes
Tove Agner, MD (Denmark)
14:45 Break & Poster Viewing (Clinical Theme)
15:15 Abstract Driven Session
(Platform Presentations)

Chair: James Taylor (USA)
Oral Abstract Presentations
(10 minute presentations with 2 – 5 minutes for questions)

3696    Skin and mucous membrane complaints related to indoor climate problems

3822    Exposure to wet-work in Australian workplaces

3826    Recognizing risk factors for persistent post-occupational dermatitis

3858    Estimating occupational exposure to skin carcinogens in Canada

3863    Inventory of the Chemicals and the Exposure of the Workers Skin to these at Two Leather Factories in Indonesia

16:45 Adjourn
17:30 Welcome Reception
Royal Conservatory of Music
273 Bloor Street West
Toronto, ON

MONDAY, JUNE 6, 2011

Plenary Session 2 From the outside in: penetration, uptake and metabolism of skin exposures and their modifying factors
The goal of the keynote(s) for this session will be to summarize the current state of knowledge (“best practice”) on how chemicals penetrate the dermal barrier, how chemicals are metabolized, how these mechanisms result in disease and the factors that modify these processes. Future expectations/challenges will be presented.

Chair: Fred Frasch (USA)

08:30 Keynote 3
Mechanisms of Chemical Effect in the Skin
Ian Kimber (UK)
09:00 Keynote 4
Permeation of Chemicals Through the Skin
Simon Wilkinson (UK)
09:30 Keynote 5
Factors Modifying the Uptake of Chemicals Through the Skin
Sanja Kezic (The Netherlands)
10:00 Break & Poster Viewing
10:45

Parallel Session #1
Exposure Models

Abstract Driven Parallel Sessions

Chair: Frank Jungbauer (The Netherlands)
(10 minute presentations with 2 – 5 minutes for questions)

3704    UPERCUT: A web-based tool to aid the identification of chemicals potentially posing a health risk through percutaneous exposure

3713    A New Database of Dermal Contact Transfer Factors

3739    How to use DPK parameters to improve cutaneous absorption knowledge for cosmetic ingredients?

3768    IH-SKINPERM an advanced skin absorption model

3818    Mathematical Modeling of Transdermal Penetration After Finite Dosing

Parallel Session #2
Exposure Uptake
Chair: Francesca Larese Filon (Italy)
(10 minute presentations with 2 – 5 minutes for questions)
3725    Metal nanoparticles skin absorption

3745    Skin Permeability from Different Vehicles:  Maximum Steady-State Flux

3810    Factors Affecting Particle Adherence to Bare Skin and Sampling Substrates

3834    Penetration Patterns of Monomeric and Polymeric 16-Hexamethylene Diisocyanate in Human Skin

3857    Single Nucleotide Polymorphisms Associated with Skin Naphthyl-Keratin Adduct Levels Among Jet Fuel Exposed Workers

12:00 Lunch
Plenary Session 3 Exposure Assessment: Models, Measurements and Monitoring

The goal of the keynote(s) for this session will be to summarize the state of knowledge on methods for assessing dermal exposure (questionnaires, measurement, biomonitoring, prediction models).  Including, the validation of new approaches and the development of scenario-based modeling techniques.

Chair: Aleks Stefaniak (USA)

13:00 Keynote 6
Dermal exposure assessment: Progress & Pitfalls
John Cherrie (UK)
13:30 Keynote 7
Models for predicting dermal exposure: development, validation and application
Dhimiter Bello (USA)
14:00 Keynote 8
Biomonitoring: Promising Targets for Measurement in Populations and Individuals
Adam Wisnewski (USA)
14:30 Break & Poster Viewing
15:15
Parallel Session #1
Exposure Sampling
Abstract Driven Parallel Sessions
Chair: Greg Day (USA)
(8 minute presentations with 2 minutes for questions)
3816    Dermal and respiratory exposure to cobalt salts in a packaging area at a base metal refinery

3821    Evaluation of a newly developed wet-work sampler for quantification of wet-work exposure in nurses: final results

3833    Measurement of dermal exposure to diisocyanates and exposure control measures in different work environments within the Swedish Motor Trade

3909    Dermal Absorption of Products of Combustion Encountered During Firefighter Training Exercises

Parallel Session #2
Methods for Exposure Assessment
Chair: Martin Roff (UK)
(8 minute presentations with 2 minutes for questions)
3811    Use of Artificial Sweat as an Extraction Solvent for Quantification of Biologically Meaningful Exposure to Chromium

3824    Simulation of removal of chemicals from skin by washing

3830    A review and evaluation of dermal exposure data in the context of dermal exposure modeling

16:30 Adjourn
18:00 to 21:00 Conference Dinner
Nethercott Lecture:
Dr. Howard Maibach

Great Hall, Hart House
University of Toronto Campus

TUESDAY, JUNE 7, 2011

Plenary Session 4 Prevention of Occupational Skin Disease – Workplace Focus
The goal of this session will be to summarize the current state of knowledge for the prevention of work-related skin disease at the shop floor level. An international panel will comment as to the feasibility of the various prevention methodologies in their jurisdiction.  Future expectations/challenges will be addressed.

Chair: Dhimiter Bello (USA)

08:30 Plenary Welcome
08:45 Keynote 9
Prevention – Workplace Focus
Diane Llewellyn (UK)
09:30 Keynote 10
Evaluating Proposed Interventions
Linn Holness (Canada)
10:00 Facilitated Interactive Discussion
10:30 Break & Poster Viewing
11:00

Parallel Session #1
Prevention in the Person

Abstract Driven Parallel Sessions
Chair: Irena Kudla (Canada)
(8 minute presentations with 2 minutes for questions)
3353    Diphoterine(R) for Sodium Hydroxide (NaOH) Skin Splash Decontamination:  In vitro and Experimental Animal Studies

3804    Predictors of dermal exposures to polycyclic aromatic compounds among asphalt paving workers

3850    The distance between theory and practice – glove use and education in the workplace

3855    Skin and Respiratory Exposure Prevention in a Clinical Population with Suspected Work-Related Disease

Parallel Session #2
Prevention in the Population
Chair: Swen John (Germany)
(8 minute presentations with 2 minutes for questions)
3827    Strategies for assessing and managing dermal exposures under the EU REACH Regulation

3828    Teledermatology in occupational skin health surveillance – diagnostic accuracy and reliability

3841    Evaluation of the awareness of latex allergy and the appropriate use of gloves among healthcare workers

3844    Raising awareness for dermatitis in the service sector: slow steps to prevention

3849    Reduction of occupational skin exposure to hazards: first voluntary agreement by European social partners in a high risk profession (hairdressing)

12:00 Lunch & Poster Viewing
Plenary Session 5 Prevention of Occupational & Environmental Skin Disease – Regulatory & Societal Focus
The goal of this session will be to summarize the current state of knowledge for the prevention of occupational & environmental skin disease at the governmental and societal levels. Various jurisdictions will present their perspectives. Future expectations/challenges will be addressed.

Chair: Irena Kudla (Canada)

13:00 The North American Perspective
Scott Dotson (USA)
13:15 The European Union Perspective
Sven John (Germany)
13:30 The Australian Perspective
Rosemary Nixon (Australia)
13:45 International Perspectives
14:15 Facilitated Discussion
14:30 Break & Poster Viewing
Plenary Session 6 General Discussion:
Fulfilling the Decade of Promise
15:15 Facilitated discussion with participation of plenary keynote speakers and the co-chairs of previous OEESC meetings
16:15 OEESC 2013 planning meeting

WEDNESDAY, JUNE 8, 2011

08:30 Workshops
Cancer
Chairs: Rosemary Nixon (Australia); Paul Demers (Canada)Discussion of the role of occupational and environmental skin exposure in the etiology of cancer.

Skin as a “sink” for carcinogens in the workplace.

Lung/Skin Interactions
Chairs: Victoria Arrandale (Canada); John Cherrie (UK); Ian Kimber (UK)

Discussion of how skin exposure may play a role in the development of asthma, including the host and environmental factors that modify these processes.

Risk Assessment/Management
Chair: Chris Packham (UK)

Interactive workshop with “situational” examples where participants will be asked to assess risk of damage to health due to actual or potential skin exposure or decide how to manage the exposure with emphasis on technical/engineering/process controls rather than PPE.

10:30 Break
11:00 Workshop Summaries
11:45 Closing Remarks
12:00 Lunch